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1 Introduction Recently, the increasing incidence and mortality of cancer have become a major threat to human health ( Ferroptosis is a novel form of iron-dependent programmed cell death, characterized by iron accumulation, lipid peroxidation and antioxidant imbalance, which extremely is distinct from necrosis, apoptosis, and autophagy (Xie et al., 2016)

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Biol 63 (1990) 69172

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